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KMID : 0882420120830050606
Korean Journal of Medicine
2012 Volume.83 No. 5 p.606 ~ p.612
Comparison of Heart Rate Variability in Kidney Transplantation and End-Stage Renal Disease Patients on Dialysis
Lee Hee-Ryong

Oh Joon-Seok
Choi Seung-Ho
Jung Peel
Ryu Tae-Hyun
Kim Sung-Min
Shin Yong-Hun
Kim Joong-Kyung
Bae Woo-Hyung
Hong Taek-Jong
Abstract
Background/Aims: Heart rate variability (HRV) is a method for evaluation of autonomic nervous system activity by expressing the balance of sympathetic and parasympathetic tones. Some studies of HRV in patients with end-stage renal disease (ESRD) have been performed in Korea. However, few have examined kidney transplantation (KT) patients. Therefore, we investigated autonomic nervous system activity by means of HRV in patients with KT due to ESRD.

Methods: We compared the pattern of cardiac sympathetic and parasympathetic activity by time- and frequency-domain analysis of HRV with 24-h Holter monitoring of 23 KT and 56 dialysis patients. Patients underwent KT between January, 2008 and June, 2011.

Results: The mean ages of KT and dialysis patients were 54.2 ¡¾ 12.3 and 53.7 ¡¾ 12.6 years, respectively. The KT group showed increased time- and frequency-domain HRV (including HRV index), very low frequency (VLF), means and standard deviations of all normal R-R intervals for all 5-min segments of the entire recording (SDNNi), low frequency (LF), LF in normalized units (LF norm), and LF to high-frequency power ratio, compared with the dialysis group.

Conclusions: Autonomic tone in patients with KT is higher than that in patients with ESRD on dialysis.
KEYWORD
Ambulatory, Electrocardiography, Heart rate, Kidney transplantation
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